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Angel A. Isidro Carrión, M.D.

Associate Professor
Department of Microbiology
 

Publications

1)    Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys. Castro Maria del R, Suarez Edu, Kraiselburd Edmundo, Isidro Angel.  Experimental Gerontology

2)    Erlotinib Inhibits Progression to Dysplasia in a Rat Model of Colitis Associated Colon Cancer Beatriz Pagan, Angel Isidro, Myrella Cruz, Yuen Ren, Domenico Coppola Jie Wu and Caroline Appleyard.    Submitted

3)   VSL#3 Probiotic Treatment Delays Transition from Inflammation to Dysplasia in a Rat Model of Colitis Associated Cancer.  Caroline B Appleyard, Myrella Cruz, Angel A. Isidro, Janelle C. Arthur, Christian Jobin and Claudio DeSimone.  Submitted

4)   Expression of S-100 Protein May Help Screen for the Transition from Inflammation to Dysplasia in Colitis Associated Colon Cancer. Jose A. Serrano, Edelmarie Rivera, Angel A. Isidro, Richard Noel Jr,Caroline Appleyard.  In Prep.

5)   Effect of a Neurokinin-1 receptor antagonist in a rat model of colitis-associated colon cáncer. Pagan B, Isidro AA, Coppola D, Chen Z, Ren Y, Wu J, Appleyard C.  Anticancer Research 2010 Sep: 30(9):3345-53.

6)    Effects of paracalcitrol and enalapril on atherosclerotic injury in mouse aortas Husain K, Suarez E, Isidro A, Ferder L, Am J Nephrol  2010;32(4):296-304 Epub 2010 Aug 17

7)   Tesaglitazar, a dual peroxisome proliferator-activated receptor agonist (PPAR alpha/gamma), improves metabolic abnormalities and reduces renal injury in obese Zucker rats. Liao J, Soltani Z,Ebenezer P, Isidro Carrion AA, Zhang R, Asghar A, Aguilar E, Francis J, Hu X, Ferder L, Reisin E. Nephron Experimental Nephrology 2010; 114(2):e61-8. Epub 2009 Nov 4

8)    Pagan B, Isidro AA, Rivera E, Coppola D, Wu J, Appleyard CB 2008 Role of Neurokin-1Receptor During the transition of Inflammation to Dysplasia in a Colitis Associated Colon Cancer Model FASEB Journal 22, No 5 A 1141

9)    Santiago C, Pagan B, Isidro AA, and Appleyard CB 2007 Prolonged Chronic Inflammation Progresses to Dysplasia in a Novel Rat Model of Colitis Associated Colon Cancer.  Cancer Research Nov 2008

10) Santiago C, Pagan B, Isidro AA, and Appleyard CB (2006) Genetic Analysis of APC, p53 and k-ras in Novel Rat Models of Colitis-Associated Dysplasia , FASEB Journal 20, No.5154.13.

11) Morse E, Gordon S, Isidro A, and Pisciotto P,  Quality Assurance in the Intensive Care Unit-Monitoring Hematocrit Orders Annals of Clinical and Laboratory Science, Vol. 20, No.5, 1990.

12) Mayoral J, Martinez G, Santiago C and Isidro A. Inflammatory Pseudotumor of the Liver:  Case Report Boletín Asociación Médica de Puerto Rico, Vol. 85, núm. 4,5,6, 1993

Abstracts

    1)   Appleyard CB, Cruz ML, Passalacqua I, Isidro AA, Isidro RA. Effect of probiotic treatment on the transition from chronic colonic inflammation to dysplasia and cancer 2011 Gastrointestinal Cancers Symposium, San Francisco, CA January 2011. Proceedings of the 2011 Gastrointestinal Cancers Symposium A385, pg 145.

    2)   Appleyard CB, Cruz ML, Isidro RA, Isidro AA, de Simone C (2011) Administration of the probiotic VSL#3 increases vitamin D receptor (VDR) expression in a model of colitis-associated colon cancer. Experimental Biology, Washington DC, April 2011 FASEB Journal 25:1122.1

    3)   Isidro RA, Cruz ML, Rodríguez VA, Isidro AA, Arroyo A, Baez-Torres A, Appleyard CB (2011) Regulation of the substance P (SP) – neurokinin-1 receptor (NK-1R) - epidermal growth factor receptor (EGFR) pathway and vitamin D receptor (VDR) in patients with colonic dysplasia. Experimental Biology, Washington DC, April 2011 FASEB Journal 25:792.18

    4)   Isidro RA, Cruz ML, Rodríguez VA, Isidro AA, Arroyo A, Baez A, Appleyard CB (2010) Neurokinin-1 Receptor (NK-1R), phosphorylated epidermal growth factor receptor (pEGFR) and cyclooxygenase-2 (Cox-2) are up-regulated in patients with colonic dysplasia. Digestive Disease Week, New Orleans, LA, May 2010 Gastroenterology 138 (5 suppl 1); S286-287.

    5)   Appleyard CB, Passalacqua I, Isidro AA, Cruz ML, Isidro RA, Rodriguez V, De Simone C (2010) Effect of the probiotic VSL#3 on the transition from chronic inflammation to dysplasia in a model of colitis-associated colon cancer. Digestive Disease Week, New Orleans, LA, May 2010 Gastroenterology 138(5 suppl 1); S-67.

    6)   Pagán B, Isidro AA, Coppola D, Wu J, Appleyard CB (2010) Role of EGFR during the transition of inflammation to dysplasia in a colitis-associated colon cancer model. AACR 101st Annual Meeting, Washington DC, April 2010 Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21

    7)   Pagán B, Isidro AA, Coppola D, Wu J, Appleyard CB (2009) Effect of targeting the neurokinin-1 receptor on the transition of chronic inflammation to dysplasia. Digestive Disease Week, Chicago IL, June 2009 Gastroenterology 136 (suppl 1); M2013.

    8)   Pagan B, Isidro AA, Rivera E, Coppola D, Wu J, Appleyard CB (2008) Role of neurokinin-1 receptor during the transition of inflammation to dysplasia in a colitis-associated colon cancer model. Experimental Biology, San Diego, CA May 2008 FASEB Journal 22, no.5. A1141.

    9)   Santiago C, Pagan B, Isidro AA and Appleyard CB (2006) Genetic analysis of APC, p53 and k-ras in novel rat models of colitis-associated dysplasia FASEB Journal 20, no.5. A219. 

    10)  Santiago C, Pagan B, Isidro AA and Appleyard CB, Histological changes and gene mutation detection in a new rat model of colitis-associated colorectal cancer (CRC).   Presented at AACR Conference “Colorectal Cancer: Molecular Pathways and Therapies” October 19-23.  Dana Point, Ca, USA.   2005
     

    11)Double Infection of Viral Hepatitis Type B among HIV Seropositive Puerto Ricans   Presented at 5th National Forum on AIDS, Hepatitis and other Blood Bourne Diseases- March-April  1992, Atlanta, Georgia.
     

    12) Isidro A, Boctor F and Wong S, A Probable Interaction between Lithium, Piroxicam and Enalapril Presenting as Lithium Toxicity-1990.