DR. IBRAHIM ALI

(1947-2005)

Ibrahim I. Ali, DVM, Ph.D.  

POSITION:

Associate Professor of Pharmacology/Toxicology and Director Biomedical Research Facility

ACADEMIC BACKGROUND :

Ph.D., Physiology and Pharmacology
College of Veterinary Medicine
The Ohio State University
June 1979

M.Sc. Physiology and Pharmacology
College of Veterinary Medicine
The Ohio State University
June 1974

D.V.M., College of Veterinary Medicine
Baghdad University
June 1970

PROFESSIONAL EXPERIENCE:

1987 – Present

Associate Professor of Pharmacology and Toxicology Director Biomedical Research Facility Ponce School of Medicine Ponce, Puerto Rico

Major Duties and Responsibilities :

Academic

Instruction in Pharmacology and Toxicology for the second year medical curriculum, including laboratory procedures and discussion.

Services

Managing and supervising all aspects of operation of the Biomedical Research Facility i.e. animal housing, feeding, care and use at the Institution.

Providing veterinary medical services.

Supervision of animal technicians including training programs.

Advisory and instruction in laboratory animal medicine and surgery, animal models and techniques in research to principle investigators, medical doctors, residents and research technicians.

Serving as a member of the Institutional Animal Care and Use Committee and reviewing all animal study protocols.

Conducting research and problems in laboratory animal medical technology and husbandry.

TEACHING RESPONSIBILITIES :

1987 – Present

Instruction in Medical Pharmacology for the second year medical students, including cardiovascular pharmacology (digitalis glycosides and antiarrhythmic drugs), antianginal, antihypertensive, anticoagulants and antilipemics drugs, local and general anesthetics, general and specific topics in toxicology. Laboratory preparation, experimental procedures and discussion were included.

Instruction in laboratory animal medicine and surgery (including handling, housing, feeding, care and use of rats, mice, rabbits, guinea pigs, dogs, cats, etc.), animal models and techniques in research to principal investigators, medical doctors, graduate students, research and animal technicians.

Research Activities: Demonstrated and supervised graduate students on using proper handling and use of laboratory animals. Advises on anesthetic and surgical animal techniques in research. Co-advisor of two dental graduate students (using rabbits and rats). Assists in supervision of rodents colonies involved in this project.

Veterinary Pathobiology 850 : Participation in teaching slide seminar, necroscopy and anatomical pathology of laboratory animals including my personal rodent colonies involved in toxicity and carcinogenicity studies to Veterinary Medicine students.

Pharmacology Dept. Seminars and Journal Club : Participation in research related topics related to laboratory animal medicine and animal models.

Drug Metabolism 852 : Participated in teaching hepatotoxicity, carcinogenicity and cardiovascular toxicity. Demonstrated animal models in toxicity and carcinogenicity of v a r i o u s environmental agents. Rats, mice, dogs and cats were involved in these studies.

Cardiovascular Pharmacology 821 : Participated in teaching cardioglycosides, antiarrhythmic drugs and antianginal drugs and Ca ++ blockers. Effect of various digitalis and antiarrhythmic drugs were shown on dogs.

Honors :

Graduate Scholarship – Ministry of Research and Higher Education, Baghdad University, College of Veterinary Medicine (represented top 5% of veterinary class)

Honorary Society of Veterinary Medicine (Phi Zeta Delta Chapter), the Ohio State University.

Awards :

Outstanding Professor of the year (1989-90) Ponce School of Medicine
Outstanding Professor of the year (1994-95) Ponce School of Medicine
Outstanding Professor of the year (1996-97) Ponce School of Medicine
Inspirational Professor of the year - Class 2001

Field of Study :

Laboratory Animal Medicine and Pathology, Physiology, Pharmacology/Toxicology.

Area of Interest :

Laboratory Animal Medicine and Pathology, Pharmacology/Toxicology

Certifications :

Educational Commission for Foreign Veterinary Graduates (ECFVG)
Veterinary National Board Examiners
Licensed to practice veterinary medicine and surgery in the State of Ohio.
Licensed to practice veterinary medicine and surgery in Puerto Rico.
United States Department of Agriculture (USDA), Veterinarian Accreditation
Board eligible for American College of Laboratory Animal Medicine and Pathology

Research Grants :

Co-Investigator, Environmental Toxicology Program-NIH-RCMI $316,122 awarded (1990-1995)
Co-Investigator, American Heart Association-Fellowship Program ($12,000/year, 3 years duration)

Publications :

Hemodynamic of Heartworm Infection, H. Mass, I. I. Ali, W. Velez and Santiago. Ann.N.Y. Academic Sciences Vol. 653, 206-210, 1992.

Toxicological Aspects of MPTP and Protection in Felines I. I. Ali, American Society of Tropical Veterinary Medicine, 1990.(abstract)

1-Methyl-4-Phenyl-1, 2, 3,-6-Tetrahydropyridine (MPTP) producesParkinson-like -syndrome in cat. I. I. Ali, Science-CienciaVol. 15, No. 2, page 39-40, 1988.

1-Methyl-4-Phenyl-1,2,3,-6-Tetrahydropyridine (MPTP) produces Parkinson-like syndrome in cat. I. I. Ali, University of Puerto Rico, Tenth Annual Research Forum page 80, 1988. (Abstract)

Aluminum Content in neonatal Rat Sera. C.H. Miller Jr., I. I. Ali, J. M. Delphia and D. Couri.

Pharmacologist Volume 28, No. 3, Page 183, 1986. (Abstract)

I-Methyl-4-Phenyl-1-1,2,3,6-Tetrahydropyridine (MPTP) produces lesions in the substantia nigra of the cat which are visible by nuclear magnetic resonance imaging (MRI) . D.E. Sharp, I. I. Ali, M. Hadjiconstantinou, P.J. Keller, W.W. Hunter and N.H. Neff. Federation Proceedings Vol. 45, No. 4, 1986. (Abstract)

Plasma mepivacaine concentrations after caudal epidural and subarachoid injection in the horse. Comparative Study, American Journal of Veterinary Research, R.T. Skarda, W.W. Muir, A.I. Ibrahim (I. I. Ali), Vol. 45, No. 10, pp. 1967-1971, 1985.

The effects of selenium on the emergence of hepatic enzyme-altered foci and liver histopathology in aflatoxin-treated rats. M. Milks, I. I. Ali, S. R. Wilt and D. Couri, Fundamental and Applied Toxicology 5, 320-326 (1985).

Spinal fluid concentration of mepivacaine in horses and procaine in cows after thoracolumbar subarachinoid analgesia. R. T. Skarda, W. W. Muir, and A. I. Ibrahim (I. I. Ali) American Journal of Veterinary Research, Vol. 46, No. 5, pp. 1020-1024, May 1985.

Hepatocellular carcinoma after chronic administration of phenobarbital (promotion) in mice. I. I. Ali, M. M. Milks and D. Couri. The Ohio Valley Chapter of the Society of Toxicology, October 14 & 15, 1983 (Abstract).

Histochemical and histopathological evaluation of the initiating and promoting effects of trichoroethylene in rat liver. M. M. Milks, I. I. Ali, and D. Couri. The Toxicologist Vol. 3, p. 35, 1983 (Abstract).

Initiating and promoting effects of 1, 2-dibromoethane on the induction of enzyme-altered foci in rat liver. M. Milks , S R. Wilt, I. I. Ali, M. A. Pereira and D. Couri. The Toxicologist, Vol. 2, p. 182, 1982 (Abstract).

Distribution of (14C) dephenylhydantioin in relation to its antidysrhythmic effect in dogs. I. I. Ali and S. Dutta, Federation of Proceedings, Vo. 36, 1012, 1977 (Abstract).

Surgical approach of the rostral cranial fossa by radical transfontal craniotomy in the dog. P. D. de Wet, I. I. Ali and D. N. Peters .Journal of the South African Veterinary Association 53: 1, pp. 40-51, 1982.

Dibromoethane effects on the induction of -glutamyl-transpeptidase positive foci in rat liver. M. M. Milks, S. R. Wilt, I. I. Ali, M. A. Pereira and D. Couri. Archives of Toxicology, 51: 27-35, 1982.

Tissue accumulation of ouabain and phenytoin, alone and in combination, and their relationship to ouabain-induced dysrhythmia. Ph.D. Dissertation, The Ohio State University, 1979.

Distribution of (14C) dephenylhydantoin in relation to i t s antidysrhythmic effect in dogs. I. I. Ali and S. Dutta, Federation of Proceedings, Vol. 36, 1012, 1977 (Abstract).

Use of systolic intervals for the monitoring of the inotropic state during post-extrasystolic potentiation. M.Sc. Thesis, The Ohio State University, 1974.

Lidocaine plasma concentration after unilateral ad bilateral cervicothorocoganglionic blockage. R.T. Skarda, I. I. Ali and W. W. Muir (Submitted).

Use of systolic intervals for the monitoring of the inotropic state during post-extrasystolic potentiation. I. I. Ali and R. Hamlin (In preparation).

A scanning transmission electron microscope (STEM) evaluation of the use of gold-tetanus complex to demonstrate sympathetic terminations in the rabbit tooth. K. Stovich, N. J. Meyers, A. L. Reader and I. I. Ali (In preparation).

Toxicity and carcinogenicity of aflotoxin alone and with selenium. S. R. Wilt, I. I. Ali and D. Couri (Submitted).

Selenium effect on initiation and promotion of tumors by benzo (a) pyrene and 12-0 tetradecanoyl phorbol acetate. S. R. Wilt, I. I. Ali, M. A. Pereira and D. Couri (Submitted).

Caffeine kinetics and seminal excretion in ram. I. I. Ali, C. Beach and N. Gerber (In preparation).

An evaluation of the retrograde transport of tetanus toxin-gold complex using the scanning transmission electron microscope (STEM) . D. Greenwald, W. J. Meyers, A. L. Rader and I. I. Ali Journal of Histochemistry-and Cytochemistry (In Press).

Distribution of phenytoin in various organs. I. I. Ali, R. Hamlin and D. Couri (Submitted for Publication).

Distribution of ouabain and in relation to its arrhythmogenic effect. I. I. Ali, R. Hamlin, S. Dutta and D. Couri (Submitted for Publication).

Dietary factors on the uptake of aluminum from drinking water in rats. C. Miller, I. I. Ali, C. Couri (In preparation).

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