The Molecular Biology Core was established in 1995 at the
Ponce School of Medicine (PSM). With the continuous support of NCRR-RCMI,
this Core activity has had a tangible impact upon the productivity of
the research faculty in human health and health disparities at PSM.
Since its inception, the MBCL has experienced tremendous growth in
capacity and number of users, so much so that there has been a 500%
increase in the number of publications and presentations citing our
This most recent cycle (2009-2014) sees the MBCL entering a new phase.
The Core will continue to place major emphasis on our fundamental
mission to provide Access, Training, and Project Development assistance
by promoting the implementation of molecular biology research in the
work of both our current faculty and future recruits. Additionally, our
mission will expand to include a greater emphasis on Service and will
add new, cutting-edge technologies. The most recent addition to the Core
is our ability to modulate gene expression (both in vitro and in vivo),
which will complement our existing capacity to perform gene expression
analyses and genetics studies. We will pursue these goals via the four
aims that follow.
Expand access to equipment and facilities, and thus continue to
application of molecular biology, genetics, and gene
expression tools by
investigators at PSMHS.
Aim 2: Provide technical support and consultation.
Aim 3: To train faculty, staff, and students in molecular research
techniques available in
Aim 4: Actively promote the development of new projects and
areas such as
molecular biology, gene expression, protein
development of model systems, and human genetics.