Leon F. Ferder, MD, PhD

Chairman and Professor
Department of Physiology and Pharmacology
1992 – 2002 Associated professor of Nephrology in the post-graduated Medical School: Title granted by the University of Buenos Aires
1996 – 1999
Professor of Pharmacology: University of Buenos Aires
1989 / 1997

Argentine Board in Nephrology: November of 1989; and recertified August of 1997.
1984 – 1991

Professor of Pharmacology: Hebrew University Argentina Bar-Ilan.
Assistant Professor of Pharmacology: University of Buenos Aires
Argentine Board in Clinical Pharmacology: University of Buenos Aires. December.
Argentine Board in Internal Medicine: December.

Fellowship in Nephrology
Brookdale University Hospital and Medical Center, New York, NY.

Residency Training in Internal Medicine:
Brookdale University Hospital and Medical Center, New York, NY.
ECFMG Exam Approved

Director of Experimental Nephrology:
Institute of Cardiovascular Research, University of Buenos Aires, School of Medicine.

Medical Doctor: University of Buenos Aires, School of Medicine.
Graduated: December.
Honor Award: School of Medicine, University of Buenos Aires.
Current Research, Teaching and Professional Appointments 2007 - Present Professor Adjunto
Universidad de Puerto Rico
Recinto Ciencias Médicas
San Juan, Puerto Rico
2006 - Present Professor Internal Medicine
Ponce School of Medicine
Ponce, Puerto Rico
2004 - Present Professor and Chairman
Department of Pharmacology and Toxicology
Ponce School of Medicine,
Ponce, Puerto Rico
2003 - Present Professor and Chairman
Department of Physiology
Ponce School of Medicine,
Ponce, Puerto Rico
2004 - Present Professor and Chairman: Department of Physiology, Pharmacology and Toxicology, Ponce School of Medicine, Ponce, Puerto Rico
2003 - Present Professor and Chairman: Department of Physiology, Ponce School of Medicine,
Ponce, Puerto Rico
1997 - Present Associate Professor: Medical Clinic Course at the Hebrea Argentina University Bar-Ilan.
1996 - Present Associate Professor: Physiology Course at the Hebrea Argentina University Bar-Ilan.
Ontarget Study Boehringer Ingelheim
Clinical Pharmacology Research: ONTARGET will assess the efficacy of the angiotensin II receptor blocker Telmisartan alone and in combination with the angiotensin converting enzyme inhibitor ramipril, and will compare these to the efficacy of ramipril alone. Endpoints will include the reduction of risk of cardiovascular mortality, stroke, myocardial infarction and hospitalization for congestive heart failure.
Role: Co-Investigator
Merck School Grant Program
Basic Research: Effect of the blockade of the renin-angiotensin system in spontaneous hypertensive rats (SHR). Aging Study.
Role: Co-Investigator

Recent Memberships of Professional Societies   2000  General Coordinator of the “National Kidney Week”, October, Argentine Society of Nephrology.
1997-1999 President of the Argentine Nephrological Association of Buenos Aires.
1989 - Present Honorary President of the Argentine Society of Pharmacology and Therapeutics.
Awards and Fellowships
2005 “Alfredo Lanari” Award. Argentine Society of Nephrology. Member Hypertension Advisory Group, American Society of Nephrology.
2004 Fellow, American Society of Nephrology (FASN).
1998 International Fellow, Council for Blood Pressure Research, American Heart Association (FAHA).

Recent Publications
2006 De Cavanagh EM, Toblli JE, Ferder L, Piotrkowski B, Stella I, Inserra F. Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipinE.Am J Physiol Regul Integr Comp Physiol. 2006 Jun;290(6):R1616-25. Epub 2006 Jan. 12.
2006 Ferder L, Inserra F, Martínez-Maldonado M. Inflammation and the Metabolic Syndrome: Role of Angiotensin II and Oxidative Stress. Current Hypertension Reports 2006, 8:191-198.

2006 Martínez-Maldonado M, Ferder L. Angiotensin II and Aging. Rev Port Nefrol Hipert 2006; 20 (4): 00-00. 2006
Toblli JE, Stella I, Mazza ON, Ferder L, Inserra F. The effect of different antihypertensive drugs on cavernous tissue in experimental chronic renal insufficiency. JN2006; Vol.19 n.4: 419-428.
2007 Ferder L The Kidney in Aging. Physiological Mini-Reviews. Vol 2, No 7, 2:43-47, February 2007. ISSN 1669-5410 (Online) ISSN 1669-5402.
2007 Ferder L., Inserra F. ¿Son los Diuréticos la droga del comienzo en el tratamiento de la Hipertensión Arterial? Revista Puertorriqueña de Medicina y Salud Pública p.47-52, Enero / Febrero.
2007 Macias Nuñez J., Robles Pérez Monteoliva NR, Herrera Pérez del Villar J, Ayus JC, Calabria F, Domínguez Gil-Hurle A, Ferder L., Grande Villoria J, Guillén Llera F, Ingaramo R, Juncos L, López-Doriga P, López Novoa ML, Martell Claros N, Martínez Maldonado M, Núñez A, Prado F, Pupi LM, Ribera Casado JM, Roldan C, Rodríguez Commes JL, Rodicio Díaz JL, Ruilope Urioste LM, Rodrigo A, Waisman G. Rcommendations for the Detention and Treatment of Hipertensión in the Elderly. Consensus Document bythe Spanish Society of Hypertension the Argentian Society of Hypertension, The Spanish Society of Geriatrics and Gerontology, The Spanish Society of Geriatric Medicine and the Spanish Society of Nephrology. Portuguese Journal of Nephrology and Hypertension. (in Press)
2007 E.M.V. de Cavahagh, F.Inserra, M.Ferder, L.Ferder. From Mitochondria to Disease: Role of the Renin-Angiotensin System. American Journal of Neprology: Am J Nephrol 2007;27:545-553.
2007 Juan Carlos Ayus, Fabiana Calabria, Alfonso Domínguez Gil-Hurley, Leon Ferder, Jesús Grande Villoria, Francisco Guillén Llera, Roberto Ingaramo, Luis Juncos, Pedro López-Doriga, José Miguel López Novoa, Nieves Martell Claros, Manuel Martinez Maldonado, Amparo Núñez, Florentino Prado, Luis Maria Pupi, Jose Manuel Rivera Casado, Cecilia Roldan, José Luis Rodríguez Commes, Jose Luis Rodicio Díaz, Luis Miguel Ruilope Urioste, Antonio Rodrigo, Gabriel Waisman. Recommendations for diagnosis and treatment of aged hypertension. Port J Nephrol Hypert 2007;27(3):270-8.
2007 Oscar A. Zimman, Jorge Toblli, Inés Stella, Marcelo Ferder, Leon Ferder, Felipe Inserra. The Effects of Angiotensin-Converting Enzyme Inhibitors on the Fibrous Envelope around Mammary Implants. Plast.Reconstr.Surg. 120:1.
2007 J. Macías, N.R. Robles y J.Herrera. J.C. Ayus, Fl Calabria, A. Domínguez, L. Ferder, J. Grande Villoria, F. Guillén, R. Ingaramo, L. Juncos, P. López-Dóriga, J.M. López Novoa, N. Martell, M.Martínez Maldonado, A. Núñez. F. Prado, L.M. Pupi, J.M. Ribera, C. Roldán, J.L. Rodicio, L.M. Ruilope, A. Rodrigo, G. Waisman y J.L. Rodríguez Commes. Recomendaciones para la detección y el tratamiento del anciano con hypertension arterial. Nefrología. Volumen 27. Número 3.
2007 Basso N, Cini R, Pietrelli A. Ferder L. Terragno NA, Inserra F. Cardiovascular Aging: Protective Effect of Long-Term Angiotensin II Inhition. Am J Nephrol. 2007;27(6):545-53 Epub 2007 Jun 8.
2007 J. Marcelo, Felipe Inserra, Stella Ines Y, Paglia Nora, Inserra Pablo IF, Ferder Leon F. Cambios Glomerulares en el Riñon Envejecido; Efecto del bloqueo del Sistema Renina. Salud Publica, Volumen IV Año I 2007.
2007 de Cavanagh EM, Ferder L, Toblli JE, Piotrkowski B, Stella I, Fraga CG, Inserta F. Renal Mitochondrial Impairment is attenuated by AT1-Blockade in Experimental Type I Diabetes. Am J Physiolo Heart Circ Physiol. 2007 Nov 16.
2007 Santiago OI, Rivera E, Ferder L, Appleyard CB. An angiotensin II receptor antagonist reduces inflammatory parameters in two models of colitis. Regul Pept. 2007 Oct 23.
Books 2006 The Local Cardiac Renin Angiotensin-Aldosterone System. Coordinators: Edward D. Frohlich, Richard N. Re., Ferder L. Chapter 16: Cellular Oxidative Stress, Aging and the Local RAS.
  2007 Comprehensive Cloniical Nephrology. Coordinators: Richard J. Johnson, John Freehally, 3rd Edition. Charpter 65 Aging and the Kidney. Ferder L, Anderson S and Johnson RJ.
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