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NAME

Kazim Husain

TITLE

Associate Professor
EDUCATION AND TRAINING
Institution and Education Degree Year(s) Field of Study
Lucknow University, India
Lucknow University, India
Kanpur University, India
Southern Illinois University School of Medicine Springfield, IL, USA		 BS
MS
PhD
Post-Doc
Training		 1978-1979
1980-1981
1982-1988
1994-1997		 Chemistry, Biology
Biochemistry
Chemistry
Pharmacology &
Toxicology
POSITIONS AND HONORS
Positions and Honors
1987-1992 Scientist B (Division of Pharmacology and Toxicology. Defense Research and Development
Establishment, Gwalior, India)
1992-1994 Scientist C (Division of Pharmacology and Toxicology. Defense Research and Development
Establishment. Gwalior, India)
1994-1997 Research Associate (Department of Pharmacology and Toxicology, SlU School of Medicine, Springfield, Illinois)
1998-2001 Assistant Professor (Department of Surgery, SIU School of Medicine, Springfield Illinois)
2002-present Associate Professor (Department of Pharmacology and Toxicology, Ponce School of Medicine, Ponce, PR)
Honors

Reviewer & Examiner: PhD (Biochemistry) Thesis "Neurotransmitters and Cholinesterase isozymes in meningitis and drug addiction" Faculty of Life Sciences, University of Bombay, India 1992.

Best Research Paper Cash Award in Life Sciences: Peripheral biochemical marker for organophosphate-induced delayed neurotoxicity. Biochem. Int. 24: 1051, 1991. DRDE, Gwalior India.

Junior Scientist Award: Outstanding Research in Pathology, Association of Scientists of Indian Origin in America (ASIOA) 1997
Selected Peer-Reviewed Publucations


Husain K. Lead-induced oxidative stress and its recovery. Cell Mol Biol. Review. In Press.

Husain K, Whitworth C, Somani SM, and Rybak LP. Partial protection by lipoic acid against carboplatin-induced ototoxicity in rats. Biomed Environ Sci. In Press.

Husain K, Mejia J, Lalla J, and Kazim S. Dose response of alcohol-induced changes in BP, nitric oxide and antioxidants in rat plasma. Pharmacol Res. Apr 2005;51(4):337-343.

Husain K, and Somani SM. Interaction of exercise and adenosine receptor agonist and antagonist on rat cardiac antioxidant defense system. Mol Cell Biochem. Feb 2005;270(1-2):209-214.

Husain K, Mejia J, Lalla J, and Kazim S. Time response of alcohol-induced alterations in BP, nitric oxide and oxidant to antioxidants balance in the plasma of rats. Exp Clin Cardiol. Winter 2004;9(4):229-234.

Husain K, Whitworth C, and Rybak LP. Time response of carboplatin-induced nephrotoxicity in rats. Pharmacol Res. Sep 2004;50(3):291-300.

Husain K. Physical conditioning modulates rat cardiac VEGF gene expression in nitric oxide–deficient hypertension. Biochem Biophys Res Commun . Aug 2004;320(4):1169-1174.

Husain K, Scott B, Whitworth C, and Rybak LP. Time response of carboplatin-induced hearing loss in rats. Hear Res. May 2004;191(1-2):110-118.

Husain K. Interaction of regular exercise and chronic nitroglycerin treatment on blood pressure and rat aortic antioxidants. Biochim Biophys Acta. Jan 2004;1688(1):18-25.

Husain K. Interaction of exercise training and chronic NOS inhibition on blood pressure, heart rate, NO and antioxidants in plasma of rats. Pathophysiology. Dec 2003;10(1):47-56.

Husain K, Whitworth C, Hazelrigg S, and Rybak L P. Carboplatin-induced oxidative injury in rat inferior colliculus. Int J Toxicol. Sep-Oct 2003;22(5):335-342.

Husain K. Interaction of Physical Training and chronic nitroglycerin treatment on blood pressure, nitric oxide and oxidants/antioxidants in the rat heart. Pharmacol Res. Sep 2003;48(3):253-261.

Husain K, Somani SM, Boley TM, and Hazelrigg SR. Interaction of physical training and chronic nitroglycerin treatment on blood pressure and plasma oxidant/antioxidant systems in rats. Mol Cell Biochem. May 2003; 247(1-2):37-44.

Husain K, Jagannathan R, Hasan Z, Trammell GL, Rybak LP, Hazelrigg SR, and Somani SM. Dose response of carboplatin-induced nephrotoxicity in rat. Pharmacol Toxicol. Aug. 2002;91(2):83-89.

Husain K and Hazelrigg S. Oxidative injury due to chronic nitric oxide synthase inhibition in rat: effect of regular exercise on the heart. Biochim Biophys Acta. May 2002;1587(1):75-82.

Husain, K. Exercise conditioning attenuates the hypertensive effects of nitric oxide synthase inhibitor in rat. Mol Cell Biochem. Feb 2002;231(1-2):129-137.

Husain K, Scott RB, Reddy KS, and Somani SM. Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system. Alcohol. Oct 2001;25(2):89-97.

Husain K, Whitworth C, Rybak LP, and Somani SM. Carboplatin-induced oxidative stress in rat cochlea. Hear Res. Sep 2001;159(1-2):14-22.

Somani SM, Husain K, Whitworth C, Malafa M, Trammell GL, and Rybak LP. Dose dependent protection by lipoic acid against cisplatin induced nephrotoxicity in rats: Antioxidant defense system. Pharmacol Toxicol. May 2000;86(5):234-241.

Reddy KS, Husain K, Schlorff EC, Scott RB, and Somani SM. Dose response of acute ethanol ingestion on antioxidant defense system in rat brain subcellular fractions. Neurotoxicology. Dec 1999;20(6):977-988.

Schlorff EC, Husain K, and Somani SM. Dose and time dependent effects of ethanol on antioxidant system in rat testes. Alcohol. Jun-Jul 1999;18(2-3):203-214.

Rybak LP, Husain K, Whitworth C, and Somani SM. Dose dependent protection by lipoic acid against cisplatin-induced ototoxicity in rats: Antioxidant defense system. Toxicol Sci. Feb 1999;47(2):195-202.

Schlorff EC, Husain K, and Somani SM. Dose and time dependent effects of ethanol on plasma antioxidant system in rat. Alcohol. Feb 1999;17(2):97-105.

Husain K and Somani SM. Interaction of exercise training and chronic ethanol ingestion on testicular antioxidant system in rat. J Appl Toxicol. Nov-Dec 1998;18(6):421-429.

Husain K and Somani SM. Effect of exercise training and chronic ethanol ingestion on cholinesterase activity and lipid peroxidation in blood and brain regions of rat. Prog Neuropsychopharmacol Biol Psychiatry. Feb 1998;22(2):411-423.

Husain K, Morris C, Whitworth C, Trammel GL, Rybak LP, and Somani SM. Protection by ebselen against cisplatin induced nephrotoxicity: Antioxidant system. Mol Cell Biochem. Jan 1998;178(1-2):127-133.

Somani SM and Husain K. Interaction of exercise training and chronic ethanol ingestion on antioxidant system of rat brain regions. J. Appl. Toxicol. Sep-Oct 1997;17(5):329-336.

Husain K and Somani SM. Interaction of exercise training and chronic ethanol ingestion on hepatic and plasma antioxidant system in rat. J Appl Toxicol. May-Jun 1997;17(3):189-194.

Husain K and Somani SM. Interaction of exercise and ethanol on hepatic and plasma antioxidant system in rat. Pathophysiology. Mar 1997;4(1):69-74.

Husain K and Somani SM. Response of cardiac antioxidant system to alcohol and exercise training in the rat. Alcohol. May-Jun 1997;14(3):301-307.

Somani SM, Husain K, Díaz-Phillips L, Lanzotti D, Kareti KR, and Trammel GL. Interaction of exercise and ethanol on antioxidant enzymes in brain regions of the rat. Alcohol. Nov-Dec 1996;13(6):603-610.

Husain K, Morris C, Whitworth C, Trammel GL, Rybak LP, and Somani SM. 4-methylthiobenzoic acid protection against cisplatin nephrotoxicity: Antioxidant system. Fundam Appl Toxicol. Aug. 1996;32(2):278-284.

Somani SM and Husain K. Exercise training alters kinetics of antioxidant enzyme in rat tissues. Biochem Mol Biol Int. Mar 1996;38(3):587-595.

Husain K. Phenyl valerate and cholinester hydrolases in the platelets of human, hen, rat and mouse. Hum Exp Toxicol. Mar 1994;13(3):157-159.

Husain K. Peripheral biochemical marker of organophosphate induced delayed neurotoxicity. Biochem Int. Aug 1991;24(6):1051-1056.

Husain K, Sikder AK, Raza SK, Das Gupta S, and Jaiswal DK. Reactivation of acetylcholinesterase activity by two new oximes in DFP intoxicated mice. Curr Sci. Dec 1990;59(24):1338-1339.

Matin MA, Husain K, and Khan SN. Modification of diazinon-induced changes in carbohydrate metabolism by adrenalectomy in rats . Biochem Pharmacol. Jun 1990;39(11):1781-1786 .

Husain K and Ansari RA. Effectiveness of certain drugs in acute malathion intoxication in rats . Ecotoxicol Environ Saf . Jun 1990;19(3):271-275 .

Matin MA, Khan SN, Husain K, and Sattar S. Effect of adrenalectomy on diazinon-induced changes in carbohydrate metabolism . Arch Toxicol. 1989;63(5):376-380.

Husain K and Ansari RA. Influence of cholinergic and adrenergic blocking drugs on hyperglycemia and brain glycogenolysis in diazinon-treated animals. Can J Physiol Pharmacol . Sep 1988;66(9):1144-1147 .

Matin MA and Husain K.Cerebral glucose and glycogen metabolism in diazinon-treated animals . J Biochem Toxicol. Fall-Winter 1987;2:265-270.

Matin MA and Husain K.Cerebral glycogenolysis and glycolysis in malathion-treated hyperglycaemic animals . Biochem Pharmacol. Jun 1987;36(11):1815-1817.

Husain K and Matin MA. Role of adrenal in the production of hyperglycemia and changes in hepatic carbohydrate metabolism in diazinon treated rats. Adv Biosci. 1987;6:101-106.

Husain K and Matin MA. Convulsions as the etiology of lactic acidosis in acute diazinon toxicity in rats. Toxicol Lett Aug. 1986;37(3):257-261.

Husain K and Matin MA. Cerebral glycolysis and glycogenolysis in diazinon treated animals. Arh Hig Rada Toksikol . Mar 1986;37(1):29-34.

Matin MA and Husain K. Striatal neurochemical changes and motor dysfunction in mipafox-treated animals. Methods Find Exp Clin Pharmacol . Feb 1985;7(2):79-81.

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