Richard J. Noel Jr.

Associate Professor

The College of Arts and Sciences, Boston College

College of Agricultural and Life Sciences University of Wisconsin - Madison

Ponce School of Medicine, Ponce, PR

Grissell Tirado, Gloria Jové, Rakesh Kumar, Richard J. Noel , Jr., Evelyn Reyes, Gladys Sepúlveda , Yasuhiro Yamamura, and Anil Kumar. Compartmentalization of drug resistance-associated mutations in a treatment-naïve HIV-infected female. AIDS Res Hum Retroviruses. June 2004;20(6):684-686. Impact Factor (as of 2003): 2.291.

Grissell Tirado, Gloria Jové, Rakesh Kumar, Richard J. Noel, Jr., Evelyn Reyes, Gladys Sepúlveda , Yasuhiro Yamamura, and Anil Kumar. Differential virus evolution in blood and genital tract of HIV-infected females: evidence for the involvement of drug and non-drug resistance-associated mutations. Virology. July 2004; 324(2):577-586. Impact Factor (as of 2003): 3.391.

Richard J. Noel, Jr . and William S. Reznikoff. Structural studies of lacUV5-RNA polymerase interactions in vitro: Ethylation interface and missing nucleoside analysis. J Biol Chem. March 2000;275(11):7708-7712. Impact Factor (2000): 7.368.

Richard J. Noel, Jr . and William S. Reznikoff. CAP, the -45 region, and RNA polymerase: three partners in transcription initiation at lacP1 in Escherichia coli. J Mol Biol. Sept. 1998;282(3):495-504. Impact Factor (1998): 5.803.

Dee Czarniecki, Richard J. Noel, Jr ., and William S. Reznikoff. The -45 Region of the Eschericihia coli lac Promoter: CAP-Dependent and CAP-Independent Transcription. J Bacteriol. 1997;179(2):423-429. Impact Factor (1997): 3.639.

Presentations

Richard J. Noel, Jr ., Gladys Chompré, Rafael A. Contreras, and Ziomara Marrero.The HIV-1 tat protein second exon provides added regulation in host cytokine gene expression (poster). 2004 International Meeting of the Institute of Human Virology. Baltimore, MD. October 31 - November 4, 2004.

Richard J. Noel, Jr. , Héctor Garcia, Santiago Collado , Suman Chaudhary, Ziomara Marrero, Grissell Tirado, and Yasuhiro Yamamura. Genital resident HIV-1 compartment in heterosexual transmission (poster). 2003 International Meeting of the Institute of Human Virology. Baltimore, MD. September 29 - October 3, 2003.

Richard J. Noel, Jr. HIV proteins and the progression to AIDS (oral presentation). Meeting to promote collaborations between the Universities of Puerto Rico and the Medical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad. August 6, 2003.

Richard J. Noel, Jr. , Suman Chaudhary, Nayra Rodríguez , Ana M. Soto, and Yasuhiro Yamamura. Phylogenetic analysis of PR and US HIV-1 pol sequences (poster). 2002. Eighth RCMI International Symposium on Health Disparities. Honolulu, HI.

Richard J. Noel, Jr. and Jaime L. Matta. The molecular mechanisms regulating the oxygen induction of MnSOD. 1999. Ponce School of Medicine, Ponce, PR.

Richard J. Noel, Jr. and Jaime L. Matta. Partial cloning of MnSOD and FeSOD from the dinoflagellate Symbiodinium microadriaticum . (poster) 1999. Meeting of The Oxygen Society, New Orleans, LA.

Richard J. Noel, Jr. and William S. Reznikoff. CAP, the -45 region, and RNA polymerase: three partners in transcription initiation at lacP1 in Escherichia coli. 1998. Ponce School of Medicine, Ponce, PR.

Richard J. Noel, Jr. and William S. Reznikoff. CAP, the -45 region, and RNA polymerase: three partners in transcription initiation at lacP1 in Escherichia coli. 1998. RCMI Molecular Biology Symposium, Ponce, PR.

Richard J. Noel, Jr. and William S. Reznikoff. CAP, the -45 region, and RNA polymerase: three partners in transcription initiation at lacP1 in Escherichia coli. 1998, University of Puerto Rico, Cayey , PR.

Dee Czarniecki, Richard J. Noel, Jr. , and William S. Reznikoff. The E. coli lac -45 region. (poster) 1997. Cold Spring Harbor - Molecular Genetics: Bacteria and Phages, Madison, WI.

Dee Czarniecki, Richard J. Noel, Jr., and William S. Reznikoff. The E. coli lac -45 region. (poster) 1997. FASEB meeting - Transcription Initiation in Prokaryotes, Saxtons River, VT.

Richard J. Noel, Jr. and Jaime L. Matta. Transcriptional regulation of the MnSOD gene of Symbiodinium microadriaticum in response to oxygen. Free Radic Biol Med. 2000;29(1):S59. Published Abstract. Impact Factor (2000): 4.116.

Richard J. Noel, Jr. and Jaime L. Matta. Partial cloning of MnSOD and FeSOD from the dinoflagellate Symbiodinium microadriaticum. Free Radic Biol Med. 1999;27(1):S22. Published Abstract. Impact Factor (1999): 4.079.

Name of individual: Richard J. Noel Jr., Ph.D.

Role: Principal Investigator

Project Number: SO6GM08239-17

Source: NIH/NIGMS/MBRS SCORE

Title of Project: Function of HIV-1 TAT 2 nd exon in cytokine dysregulation

Dates of award: 06/01/02-05/31/05

This is a study of the in vitro properties of three forms of Tat (Tat72, Tat86, and Tat101) to alter expression of MCP-1, IL-8, and TNF-alpha in U87MG cells. The three aims are to examine the dose response, examine the time course, and finally, to determine the location of action (intracellular/extracellular or extracellular only).

Name of individual: Richard J. Noel Jr., Ph.D.

Role: Principal Investigator

Project Number: G12RR003050

Source: NIH/NCRR/RCMI

Title of Project: Viral Sequences in Pediatric HIV infection in PR

Dates of award: 10/01/03-06/30/08

Aimed at assessing the viral correlates of pathogenicity, this is a study of the viral sequence variation at three loci in two groups of Puerto Rican HIV-1 infected children.